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Yu Matsumoto Selected Research

cyclic arginine-glycine-aspartic acid peptide

10/2017cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells.
12/2016Targeted systemic delivery of siRNA to cervical cancer model using cyclic RGD-installed unimer polyion complex-assembled gold nanoparticles.
12/2015cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis.
6/2015Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas.
9/2014Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors.
3/2014Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors.
10/2013Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier.
6/2012Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection.

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Yu Matsumoto Research Topics

Disease

37Neoplasms (Cancer)
02/2022 - 01/2011
5Lung Neoplasms (Lung Cancer)
02/2021 - 02/2014
5Uterine Cervical Neoplasms (Cancer of the Cervix)
12/2016 - 09/2014
4Neoplasm Metastasis (Metastasis)
12/2015 - 09/2013
3Obesity
01/2022 - 01/2020
3Pancreatic Neoplasms (Pancreatic Cancer)
01/2022 - 01/2012
3Disease Progression
10/2021 - 12/2018
3Carcinoma (Carcinomatosis)
10/2021 - 11/2014
3Inflammation (Inflammations)
01/2019 - 09/2014
3Infections
12/2018 - 06/2012
3Hemorrhage
12/2018 - 10/2010
2Tuberous Sclerosis (Bourneville's Disease)
01/2021 - 12/2020
2Pneumonia (Pneumonitis)
01/2021 - 08/2019
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
08/2019 - 01/2019
2Lymphatic Metastasis
12/2015 - 05/2015
2Dehydration (Water Stress)
09/2015 - 10/2013
2Glioblastoma (Glioblastoma Multiforme)
06/2015 - 10/2013
1Iron Overload
07/2022
1Drug-Related Side Effects and Adverse Reactions
07/2022
1Hyperphosphatemia
07/2022
1Chronic Renal Insufficiency
07/2022
1Overweight
02/2022
1Respiratory Insufficiency (Respiratory Failure)
02/2022
1Pulmonary Alveolar Proteinosis
02/2022
1Hepatocellular Carcinoma (Hepatoma)
01/2022
1Stomach Neoplasms (Stomach Cancer)
11/2021
1Emergence Delirium
10/2021
1Microsatellite Instability
10/2021
1Confusion (Bewilderment)
10/2021
1Liver Diseases (Liver Disease)
06/2021
1Thrombosis (Thrombus)
02/2021
1Venous Thromboembolism
02/2021
1Disseminated Intravascular Coagulation
02/2021
1Hearing Loss (Hearing Impairment)
01/2021
1Hypoxia (Hypoxemia)
01/2021
1Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia)
01/2021

Drug/Important Bio-Agent (IBA)

17MicellesIBA
10/2021 - 01/2011
9Pharmaceutical PreparationsIBA
01/2022 - 01/2011
9LigandsIBA
08/2020 - 10/2013
8cyclic arginine-glycine-aspartic acid peptideIBA
10/2017 - 06/2012
8Small Interfering RNA (siRNA)IBA
12/2016 - 01/2012
7PlatinumIBA
08/2020 - 01/2011
5Proteins (Proteins, Gene)FDA Link
01/2022 - 03/2014
4IntegrinsIBA
10/2017 - 10/2013
3NivolumabIBA
11/2021 - 12/2018
3Cisplatin (Platino)FDA LinkGeneric
02/2021 - 01/2012
3Immune Checkpoint InhibitorsIBA
08/2019 - 12/2018
3Peptides (Polypeptides)IBA
09/2014 - 10/2013
2pembrolizumabIBA
10/2021 - 08/2019
2B7-H1 AntigenIBA
10/2021 - 08/2019
2Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2021 - 06/2016
2Anti-Bacterial Agents (Antibiotics)IBA
01/2021 - 08/2019
2arginyl-glycyl-aspartic acidIBA
10/2017 - 10/2013
2GoldIBA
12/2016 - 09/2014
21-phenyl-3,3-dimethyltriazene (PDT)IBA
05/2016 - 02/2014
2Photosensitizing Agents (Photosensitizers)IBA
05/2016 - 11/2014
23-hydroxyaspartic acidIBA
09/2015 - 10/2013
2DisulfidesIBA
09/2014 - 01/2012
2PolymersIBA
09/2014 - 01/2012
1ferric citrateIBA
07/2022
1CalciumIBA
07/2022
1Hemoglobins (Hemoglobin)IBA
07/2022
1Transferrin (beta 2 Transferrin)IBA
07/2022
1IronIBA
07/2022
1Ferritins (Ferritin)IBA
07/2022
1Phosphates (Orthophosphate)IBA
07/2022
1Parathyroid Hormone (Parathormone)IBA
07/2022
1Phosphorus (Red Phosphorus)IBA
07/2022
1Glycoproteins (Glycoprotein)IBA
02/2022
1LeptinIBA
02/2022
1LactoferrinIBA
02/2022
1sulforaphaneIBA
01/2022
1isothiocyanic acidIBA
01/2022
1Fatty Acid Synthases (Fatty Acid Synthase)IBA
01/2022
1Acetyl-CoA CarboxylaseIBA
01/2022
1Radiation-Sensitizing AgentsIBA
01/2022
1Chloroquine (Aralen)FDA LinkGeneric
10/2021
1Indocyanine Green (Cardio-Green)FDA LinkGeneric
06/2021
1fibrin fragment D (D-dimer)IBA
02/2021
1Trimethoprim (Proloprim)FDA LinkGeneric
01/2021
1Insulin (Novolin)FDA Link
01/2021
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2021
1PowdersIBA
01/2021
1Oxygen (Dioxygen)IBA
01/2021
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2021
1Fatty Acids (Saturated Fatty Acids)IBA
01/2021
1trans-crotonin (CTN)IBA
01/2021

Therapy/Procedure

20Therapeutics
01/2022 - 01/2011
5Lasers (Laser)
10/2021 - 10/2013
4Intravenous Injections
10/2016 - 06/2012
2Anesthesia
10/2021 - 12/2016
2Drug Therapy (Chemotherapy)
02/2021 - 08/2019
1Renal Dialysis (Hemodialysis)
07/2022
1Peritoneal Dialysis
07/2022
1General Anesthesia
02/2022
1Radiotherapy
01/2022
1Precision Medicine
01/2022
1Minimally Invasive Surgical Procedures
06/2021
1Reoperation
01/2021
1Myringoplasty
01/2021